課程資訊
課程名稱
專題討論
Seminar 
開課學期
104-2 
授課對象
生化科技研究所  
授課教師
楊啟伸 
課號
BST7000 
課程識別碼
B22 M0020 
班次
04 
學分
全/半年
半年 
必/選修
必修 
上課時間
星期一8,9(15:30~17:20) 
上課地點
農化一第六 
備註
必修4學期。與黃慶璨、張麗冠、陳進庭、林晉玄、吳承合開
限碩士班以上
總人數上限:42人 
Ceiba 課程網頁
http://ceiba.ntu.edu.tw/1042BST7000_04 
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課程概述

專題討論 

課程目標
待補 
課程要求
待補 
預期每週課後學習時數
 
Office Hours
 
指定閱讀
待補 
參考書目
待補 
評量方式
(僅供參考)
   
課程進度
週次
日期
單元主題
第1週
2/22  課程說明:期刊文章選擇、實驗流程、C123原則檢驗 
第2週
2/29  【學生課程準備週】 
第3週
3/07  <mark><b>《博士班學生期刊文章報告》</mark></b>
【鄧福勝】
Impact of Bacterial-Fungal Interactions on the Colonization of the Endosphere.
<i><b>Trends Plant Sci. 21:230-242(2016)</i></b>
【黃柄翰】
Enhancer RNAs and regulated transcriptional programs
<i><b>Trends in Biochemical Sciences, 39:170-182 (2014)</i></b> 
第4週
3/14  【沈縵】<br />Current applications of nanoparticles in infectious diseases
<b><i>Journal of Controlled Release 224 (2016) 86–102</b></i>.
<mark><b>《碩一學生期刊文章報告》</mark></b>
【張景翔】
Engineering Complex Synthetic Transcriptional Programs with CRISPR RNA Scaffolds
<b><i>Cell 160:339-350 (2015)</b></i>. 
第5週
3/21  【陳政良】
Redox cycling of Fe(II) and Fe(III) in magnetite by Fe-metabolizing bacteria.
<i><b>Science 347:1473-1476 (2015)</i></b>
【洪凱琳】
Multiplexable, locus-specific targeting of long RNAs with CRISPR-Display
<b><i>Nature Methods 12:664-670 (2015)</b></i>. 
第6週
3/28  【陳紀元】
Filamentous Bacteriophage Promote Biofilm Assembly and Function.
<i><b>Cell Host Microbe, 18:549-59 (2015) </b></i>.
【林庭安】
Cell-to-Cell Transmission of HIV-1 Is Required to Trigger Pyroptotic Death of Lymphoid-Tissue-Derived CD4 T Cells
<b><i>Cell Rep. 12:1555-1563 (2015)</b></i>. 
第7週
4/04  (( 放 假 )) 
第8週
4/11  【蔡孟羲】
Programmable control of bacterial gene expression with the combined CRISPR and antisense RNA system
<i><b>Nucleic Acids Res. 2016 Feb 2. [Epub ahead of print]</i></b>
【何新榮】
Exogenous Alanine and/or Glucose plus Kanamycin Kills Antibiotic-Resistant Bacteria
<i><b>Cell Metabolism 21:249–261(2015)</i></b>
 
第9週
4/18  【李依依】
A Novel Blood-Brain Barrier Co-Culture System for Drug Targeting of Alzheimer’s Disease: Establishment by Using Acitretin as a Model Drug
<i><b>PLoS ONE 9(3): e91003 (2014)</i></b>
【荊士瑋】
Intestinal REG3 Lectins Protect against Alcoholic Steatohepatitis by Reducing Mucosa-Associated Microbiota and Preventing Bacterial Translocation.
<b><i>Cell Host Microbe 19:227-239 (2016)</b></i> 
第10週
4/25  【張煜】<br />Sensor histidine kinase is a β-lactam receptor and induces resistance to β-lactam antibiotics<br /><b><i>PNAS 113:1648–1653 (2016)</b></i>.
【胡哲銘】
Self-induced metabolic state switching by a tunable cell density sensor for microbial isopropanol production
<b><i>Metabolic Engineering 30:p7-p15 (2015)</b></i>
 
第11週
5/02  【林小琪】
Cell Wall N-Linked Mannoprotein Biosynthesis Requires Goa1p, a Putative Regulator of Mitochondrial Complex I in <i>Candida albicans</i>.
<b><i>PLoS One 11(1):e0147175 (2016) </b></i>
【陳昱嘉】
Cross-Kingdom Chemical Communication Drives a Heritable, Mutually Beneficial Prion-Based Transformation of Metabolism
<i><b>Cell 158:1083-1093 (2014)</i></b> 
第12週
5/09  <mark><b>《碩二學生研究論文報告》</mark></b>
【黃儀真】
結合光動力殺菌與Fluoconazole在白色念珠菌的殺菌效果探討
Combination of Photodynamic inactivation and Fluconazole against <i>Candida albicans</i>
【陳則堯】 
第13週
5/16  【黃元祈】
Investigation of a possible simultaneously light-driven inward proton and chloride pump, NpHR, from <i>Natronobacterium pharaonis</i>
【簡琇羽】
An a-pheromone transporter Hst6 is involved in pheromone-induced cell adhesion, mating and white-opaque transition of <i>Candida albicans</i>
 
第14週
5/23  【翁筠婷】
TRIM5α Induces Degradation of Epstein-Barr Virus Protein Rta by Autophagy in Lytic Cycle
【吳智宇】
Immediate-early genes wssv108 of white spot syndrome virus(WSSV) regulates immediate-early genes promoters activity 
第15週
5/30  【殷 &#32675;】
Rta參與EB病毒BRLF1-BZLF1雙基因mRNA轉譯起始之機制
【林俞均】
Expression of recombinant T4 endonuclease V by fermentation in <i>Pichia pastoris</i>. 
第16週
6/06  【王開立】
白蝦YY1及Dorsal蛋白質協同調控白點症病毒極早期基因的表現
Regulation of the immediate-early gene of white spot syndrome virus <i>by Litopenaeus vannamei</i> YY1 and Dorsal
【黃湘燕】
<i>Bacillus cereus</i>產生羽毛分解酵素之研究 
第17週
6/13  【侯健睿】
Insight into the function of six transcriptional factors in regulation of hyphae formation and biofilm development in <i>Candida tropical</i>
【張芝蓉】
Establishment of stable heterologous gene expression system by mating strategies
in <i>Flammulina velutipes</i>